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Disodium Inosinate
Cautionary Ingredient - This ingredient appears to be problematic.
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What it is:
Synthetic Flavor enhancer: Used in baked goods, ice cream, confections, dairy products, meats, and seasonings.
What we know:
Disodium inosinate, chemical formula is the disodium salt of inosinic acid. It is a food additive often found in instant noodles, potato chips, and a variety of other snacks. It is used as a flavor enhancer, in synergy with monosodium glutamate (also known as MSG; the sodium salt of glutamic acid) to provide the umami taste. As it is a fairly expensive additive, it is not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, parmesan cheese or yeast extract. It is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5'-ribonucleotides.

The FDA has listed this additive as permitted for direct addition to food for human consumption (FDA regulation 21CFR172.535).

Careful studies have shown that some people are sensitive to MSG. Reactions include headache, nausea, weakness, and burning sensation in the back of neck and forearms. Some people complain of wheezing, changes in heart rate, and difficulty breathing.
Other Names:
Disodium 5'-inosinate; Sodium 5'-inosinate; Disodium inosine 5'-monophosphate; Inosine 5'-(disodium phosphate); Sodium inosinate; Disodium IMP; IMP disodium salt
Information Provided By:
M. Ash, I. Ash, Handbook of food additives (Synapse Information Resources, Endicott, NY, ed. 2nd, 2002), pp. xiii, 1079